Sterols and Triterpenes From the Fruit of Annona muricata Linn.

Authors

  • Consolacion Y. Ragasa Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University
  • Oscar B. Torres Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University
  • Geneveve Soriano Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University
  • Chien-Chang Shen National Research Institute of Chinese Medicine

Keywords:

Annona muricata, Annonaceae, sitosterone, β-sitosteryl fatty acid ester, β-sitosterol, β-amyrin, squalene

Abstract

Annona muricata Linn., commonly known as guyabano, is a wellknown medicinal tree. The bioactivities of A. muricata are varied,
but the commonly isolated compounds are acetogenins which exhibit anticancer properties. This study reports on the isolation of the sterols: β-sitosterone (1), β-sitosteryl fatty acid ester (2) and β-sitosterol (3); and the triterpenes: β-amyrin (4), β-amyrin (5) and squalene (6) from the dichloromethane extract of the freeze-dried fruit of Annona muricata Linn. Compounds 1-6 were isolated by silica gel chromatography and identified by NMR spectroscopy. These compounds were reported to possess diverse bioactivities.

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Published

2022-10-06

How to Cite

Ragasa, C. Y., Torres, O. B., Soriano, G., & Shen, C.-C. (2022). Sterols and Triterpenes From the Fruit of Annona muricata Linn. Silliman Journal, 54(1). Retrieved from https://sillimanjournal.su.edu.ph/index.php/sj/article/view/136